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Several non-governmental organisations are calling for greater risk evaluations or, in the case of Canada's ETC Group, a nanotech research moratorium. They, and others including the US-based Centre for Responsible Nanotechnology, have raised concerns about the following aspects of nanotechnology:
• The toxicity of bulk material, such as solid silver, does not help predict the toxicity of nanoparticles of that same material.
• Nanoparticles have the potential to remain and accumulate in the environment.
• They could accumulate in the food chain.
• They could have unforeseen impacts on human health.
• The public has not been sufficiently involved in debates on the applications, uses, and regulation of nanotechnology.
• 'Grey goo': Tiny robots generated with nanotechnology could acquire the ability to self-replicate.
• If the rich countries are the main drivers of the development of nanotechnology, applications which benefit developing nations will be side-lined.
• Unless rapid action is taken, research into nanotechnology could progress faster than systems can be put in place to regulate its applications and their uses.
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